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. Author manuscript; available in PMC: 2023 Apr 3.
Published in final edited form as: Nat Methods. 2022 Oct 3;19(10):1234–1242. doi: 10.1038/s41592-022-01605-0

Figure 2. Riboswitch affinity predictions reveal similar package ranking.

Figure 2.

(A) Representative scatterplots for the Ribologic-FMN dataset of experimental vs. predicted values of KMS2−lig. (B) Calculating the Z-scores of Pearson correlation coefficients across 12 independent datasets of riboswitches result in an overall ranking (C) consistent with the Chemical Mapping dataset. Error bars represent 95% confidence interval of the mean obtained over 1000 iterations of bootstrapping over n=12 independent experiments of 7,228 independent constructs total.