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. 2023 Jan 10;56(1):78–92.e6. doi: 10.1016/j.immuni.2022.12.004

Figure 1.

Figure 1

MAIT cells accelerate wound closure

Full-thickness wounds were performed on B6-MAITCAST mice and splinted with a silicone ring to prevent epithelial contraction.

(A) Longitudinal follow-up of wound surface (ratio wound over ring areas) for Mr1+/+ (black circle) or Mr1−/− (gray square) littermates. Blind experiment. t test.

(B) Wound surface at days 4 and 7. Pooled data from four independent experiments (n4 = 13; n7 = 9). Mann-Whitney test.

(C) Hematoxylin and eosin-saffron staining of Mr1+/+ and Mr1−/− wounds 4 days after excision and longitudinal follow-up of wound gap (distance between the epithelial tongues). Pooled data from two independent experiments analyzed blindly (n1 = 2/3; n2 = 3/4; n4 = 5). Mann-Whitney test.