Effects of DoMRE on the inflammatory factors TNF-α, IL-6, and IL-1β of colonic mucosa in HUA rats. (a) Intestinal IL-1β IHC pictures (×400). (b) Colon IL-16 OD value. (c) Ileum IL-1β OD value. (d) Duodenum IL-16 OD value. (e) Intestinal IL-6 IHC pictures (×400). (f) Duodenum IL-6 OD value. (g) Ileum IL-6 OD value. (h) Colon IL-6 OD value. (i) Intestinal TNF-α IHC pictures (×400). (j) Colon TNF-5 OD value. (k) Ileum TNF-α OD value. (l) Duodenum TNF-5 OD value. Semiquantitative analysis of TNF-α, IL-6 and IL-1β protein expressions in duodenum ileum, and colon were presented as IOD/area. NC, normal control group; MC, model control group; DoMRE-L, low dose of DoMRE group; DoMRE-H, high dose of DoMRE group. The data were expressed as mean ± SD of 8 rats in each group. #P < 0.05; ##P < 0.01, compared with NC group; ∗P < 0.05; ∗∗P < 0.01, compared with MC group.