FIG. 1.

Immune response and protective efficacy of E. faecalis 12030 CP antigen. (a) Mean and standard deviation (error bars) of antibody titer to the CP antigen after three or four immunizations of 10 mice with purified antigen. (b) CFU of E. faecalis 12030 per gram of liver, spleen, or kidney of mice immunized with enterococcal CP antigen (immune) or P. aeruginosa MEP (nonimmune) after challenge with 6 × 10⁶ CFU of E. faecalis 12030. Each point represents the bacterial counts from a single mouse. Bars indicate the median CFU/gram of tissue for the group. P was <0.001 for comparisons in all three tissues between immune and control animals as determined by the Mann-Whitney U test.