Fig. 1.

Platelet lysate (PL) can support expansion of dermal fibroblasts ex vivo. Primary adult fibroblast proliferation in media supplemented with 0.5%, 1%, 2% and 4% PL, compared to 4% FBS were measured by a cell counting and b Alamar Blue on day 2, day 4 and day 6 post-seeding. c Fibroblasts were kept in media supplemented with 0.5% PL, 1% PL, 2% PL, 4% PL or 4% FBS for over 3 months. Cell numbers were determined at each split. Values represent mean + / − SEM in each group (n = 3 per group). Data analysed using an unpaired t-test