FIGURE 2.

Flowchart for inclusion in the ancillary study. Participants were recruited to a study of low milk supply (n = 46), but 3 declined participation in future analysis. A small number (n = 8) were assigned to metformin treatment as part of a pilot clinical trial. All participants in the low milk supply study were categorized by milk production as very low (<300 mL/d; n = 23) or moderate (≥300 mL/d; n = 20). External controls were recruited who were exclusively breastfeeding infants with healthy weight gain (n = 18). RCT, randomized controlled trial.