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. 2022 Dec;14(12):4815–4827. doi: 10.21037/jtd-22-1533

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2022 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The expression of INTS7 in LUAD tissues. (A) INTS7 mRNA expression analysis of LUAD samples and adjacent normal samples by TCGA. (B) The protein expression levels of INTS7 based on CPTAC. (C) mRNA expression of INTS7 at different T stages in LUAD patients from TCGA. (D) Immunohistochemical analysis of INTS7 expression in paired LUAD and normal tissues. (E) The OS (left) and DFS (right) rates of LUAD patients with high or low mRNA expression levels of INTS7 from TCGA. *, P<0.05, ***, P<0.001. INTS7, integrator complex subunit 7; LUAD, lung adenocarcinoma; TCGA, The Cancer Genome Atlas; CPTAC, Clinical Proteomic Tumor Analysis Consortium; OS, overall survival; DFS, disease-free survival; TPM, transcripts per million reads, FPKM, Fragments Per Kilobase of exon model per Million mapped fragments.