. 2022 Jul 5;13(1):127–138. doi: 10.1016/j.jceh.2022.06.013

Table 1.

Main Studies Evaluating Early Liver Transplantation (LT) for Severe Alcohol-related Hepatits (AH).

Study	N (patients with severe AH transplanted)	Study design	Control group	Survival rate in patients transplanted (in bold) and in patients not transplanted (light)				Any alcohol relapse post-LT
Study	N (patients with severe AH transplanted)	Study design	Control group	6-month survival	1-year survival	2-year survival	3-year survival	Any alcohol relapse post-LT
Mathurin et al., 2011²²	26	Prospective	Patients with severe AH not transplanted	77% 23%		71% 23%		12%
Im et al., 2016²⁴	9	Retrospective	Patients with severe AH not transplanted	89% 11%				22%
Lee et al., 2017⁹³	17	Retrospective	Alcohol-related cirrhosis with ≥6 months abstinence	100% 88%				23.5%
Weeks et al., 2018⁹⁴	46	Retrospective	Alcohol-related cirrhosis who received liver transplants under standard protocols with at least 6 months sobriety.		97% 100%			−28% in patients with severe AH −24% in patients with alcohol-related cirrhosis
Lee et al., 2018²³	147	Retrospective	None		94%		84%	−25% (at one year) −34% (at 3 years)
Louvet et al., 2022⁹²	68	Prospective	- Patients with severe AH not transplanted - Patients with alcohol-related cirrhosis listed for liver transplantation after at least 6 months of abstinence			89.7% 88,2%		−34% at 2 years (patients with AH) −25% at 2 years (in patients with alcohol related cirrhosis)
Germani et al., 2022⁹⁶	16	Retrospective	Patients with severe AH not transplanted	100% 41%	100% 41%	100% 38%	100% 35%	12.5%

Abbreviations: AH, Alcohol-related Hepatitis; LT, Liver Transplantation.