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. 2022 Sep 28;3(3):175–187. doi: 10.12336/biomatertransl.2022.03.002

Table 1. Comparison of the characteristics of different stem cells.

Embryonic stem cells Induced pluripotent stem cells Somatic or adult stem cells
Source Inner cell mass of the blastocyst Reprogrammed somatic cells Tissue-specific protocols from different tissues
Differentiation potential Can differentiate into cell types of all three germ lineages Can differentiate into cell types of all three germ lineages Can only differentiate into limited cell types
Self-renewal Complete Complete Limited
Proliferative capacity Strongest Powerful Weak and cannot be maintained for a long periods
Tumorigenicity Yes Yes No
Ethical controversy Yes No No