Table 2. Characteristics of the major types of extracellular vesicles.

Vesicles	Size (nm)	Density (g/mL)	Origin	Markers	Membrane permeability
Exosomes	30–150	1.13–1.18	Endosomes	Tetraspanins (CD9, CD63, CD81), TSG101, ALIX	Impermeable
Microvesicles	200–1000	1.16–1.19	Budding of plasma membrane	Integrins, selectins, CD40	Impermeable
Apoptotic bodies	>1000	1.16–1.28	Release after apoptosis	Propidium iodide positive Phosphatidylserine DNA fragmentation	Permeable

Note: ALIX: apoptosis-linked gene 2-interacting protein X; TSG101: tumour susceptibility gene 101.