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Uptake of fluorescent-labeled mannose-siRNA conjugate by macrophages and dendritic cells
Cy3-labeled hexa-mannose-siCD45, tetra-mannose-siCD45, or tetra-GalNAc-siCD45 were incubated with M1, M2, iDC, or mDC derived from human CD14+ monocytes. The MFI of Cy3 was quantified using flow cytometry to determine the uptake of each conjugate. The error bars represent standard deviation.
