Fig. 6.

TDCA diet increases NK cells but decreases NK cells’ activity via increasing Qa-1 expression. Mice were fed either a chow diet (control) or a chow diet containing 0.4% TDCA for 10 weeks. A NK1.1+ cells as % of total CD45+ cells. B NKp46+ cells as % of total CD45+ cells. C NKp46+ NKG2D+ cells as % of total NKP46+ cells. D Qa-1+ cells as % of total TCRβ+ cells E Qa-1+ cells as % of total CD8+ cells in the IELs, PP, LP, and spleen of female (left panel) and male (right panel) mice. Data were expressed as mean ± SEM. *p<0.05, **p<0.01. Statistical analysis was performed by a two-tailed unpaired Student’s t test