Figure 6. Antibody Binding to Phages Pre- and Post-Phage Treatment Demonstrates Late Development of Anti-phage Neutralizing Antibodies.
(A) Half maximal titers of IgG antibodies in pre-phage serum collected at day -1 and indicated times post-phage initiation for phages BPsΔ33HTH_HRM10 and D29_HRMGD40. Titers for two to six replicates are displayed as white data points on top of a mean bar ± s.d.
(B) Serum collected 1 day prior to phage initiation and indicated times post-phage initiation were tested for phage neutralization of BPsΔ33HTH_HRM10, D29_HRMGD40, and a control phage Fionnbharth Δ45–47. Data are representative of duplicate or triplicate assays.