TABLE 3.
In vivo protective effect in passive transfer experimentsa
| Ab used | Sporozoite IFAT result for:
|
No. infected/no. tested:
|
|||
|---|---|---|---|---|---|
| P. falciparum | P. yoelii | Expt 1 | Expt 2 | Total | |
| Anti-β-Gal-DG729 | + | + | 0/2 | 0/2 | 0/4 |
| Anti-β-Gal-DG671 | + | − | 2/2 | 2/2 | 4/4 |
| None | 2/2 | 2/2 | 4/4 | ||
a
One hundred micrograms of human anti-β-Gal-DG729 (LSA3) or anti-β-Gal-DG671 (SALSA) Ab per ml was added to 150 P. yoelii sporozoites, in a final volume of 200 μl/mouse, and injected into the tail vein of BALB/c mice. Parasitemia was recorded from day 4 to day 21 after challenge.