Table 3.
Pearson correlation coefficients for the relationship between change in hypothesized intervention effect mediators and change in log-transformed biomarker level
| Hypothesized Intervention Effect Mediators | Change in Log-Transformed Biomarker Level | |||
|---|---|---|---|---|
| CRP | SAA | ICAM-1 | VCAM-1 | |
| Δ Bodyweight | 0.40 | 0.32 | 0.18 | — |
| Δ Fat Mass | 0.37 | 0.34 | 0.14 | — |
| Δ Visceral Adipose Tissue | 0.31 | 0.19 | — | — |
| Δ Subcutaneous Adipose Tissue | 0.31 | 0.28 | — | — |
| Δ Lean Mass | 0.30 | 0.24 | 0.21 | — |
| Δ Appendicular Lean Mass | 0.23 | — | — | — |
| Δ Aerobic Fitness Capacity | — | — | — | — |
| Δ Bench Strength | — | — | — | — |
| Δ Leg Strength | — | — | — | — |
CRP, C-Reactive Protein; SAA, Serum Amyloid A; ICAM-1, Intercellular Adhesion Molecule-1; VCAM-1, Vascular Cell Adhesion Molecule-1. All correlations shown were statistically significant (p<0.05). The symbol “—” denotes absence of significant correlation.