Table 2:
Hazard ratios (95% CI) for risk of frailty according to categories of cumulative average of leisure time physical activity MET hour/wk in women ≥60y
| Quintiles | |||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | p trend | Per 3 MET hr/wk | |
| Total physical activities | |||||||
| Median MET (hour/wk) | 3.2 | 8.6 | 14.7 | 23.3 | 42.2 | ||
| No. of cases | 5598 | 3757 | 3052 | 2386 | 1686 | ||
| Person-time | 221,776 | 223,719 | 223,740 | 224,409 | 224,685 | ||
| Age adjusted | 1 | 0.68 (0.65, 0.71) | 0.56 (0.53, 0.58) | 0.44 (0.42, 0.47) | 0.32 (0.31, 0.34) | <0.001 | 0.92 (0.92, 0.93) |
| Multivariablea | 1 | 0.78 (0.75, 0.81) | 0.69 (0.66, 0.72) | 0.59 (0.56, 0.62) | 0.48 (0.45, 0.50) | <0.001 | 0.95 (0.95, 0.95) |
| Moderate activities | |||||||
| Median MET (hour/wk) | 1.1 | 3.6 | 6.9 | 11.3 | 20.3 | ||
| No. of cases | 5474 | 3793 | 3174 | 2412 | 1626 | ||
| Person-time | 221,978 | 223,048 | 229,698 | 221,618 | 221,987 | ||
| Age adjusted | 1 | 0.69 (0.66, 0.72) | 0.57 (0.55, 0.60) | 0.45 (0.43, 0.47) | 0.31 (0.29, 0.33) | <0.001 | 0.85 (0.84, 0.85) |
| Multivariablea | 1 | 0.80 (0.76, 0.83) | 0.72 (0.69, 0.76) | 0.63 (0.60, 0.66) | 0.51 (0.48, 0.54) | <0.001 | 0.91 (0.90, 0.92) |
| Vigorous activities | |||||||
| Median MET (hour/wk) | 0.0 | 2.3 | 5.5 | 11.1 | 25.5 | ||
| No. of cases | 5052 | 3468 | 3183 | 2708 | 2068 | ||
| Person-time | 249,643 | 193,390 | 225,813 | 226,164 | 223,319 | ||
| Age adjusted | 1 | 0.84 (0.80, 0.87) | 0.72 (0.69, 0.76) | 0.62 (0.59, 0.64) | 0.48 (0.46, 0.51) | <0.001 | 0.93 (0.93, 0.94) |
| Multivariablea | 1 | 0.91 (0.87, 0.95) | 0.85 (0.81, 0.89) | 0.80 (0.76, 0.84) | 0.75 (0.71, 0.79) | <0.001 | 0.97 (0.97, 0.98) |
a
Multivariable adjusted for age, estimated lean body mass, estimated fat mass, body weight, energy intake, alcohol intake, AHEI-2010 score, post-menopausal hormone use, smoking, highest degree earned, use of the following medications: aspirin, beta blockers, hydrochlorthiazide, ACE inihibitors, calcium channel blockers, other antihypertensive medications, insulin, oral hypoglycemics, lipid lowering medication. Moderate and vigorous activities were mutually adjusted for each other.