TABLE 1.
Precursor frequencies of IFN-γ-and IL-4-producing cells responding to malarial antigens
| Day of infection | Genotype of mouse | CD4+-T-cell precursor frequencya (per 106 cells)
|
||
|---|---|---|---|---|
| IFN-γ | IL-4 | Help for Ab production | ||
| 7 | C1qa−/− | 758.2 ± 111.4 | 154.0 ± 77.0 | 102.6 ± 4.05 |
| C1qa+/+ | 545.5 ± 46.0 | 128.7 ± 68.1 | 151.5 ± 12.5 | |
| 28 | C1qa−/− | 326.7 ± 22.7 | 87.7 ± 23.3 | 511.6 ± 123.4 |
| C1qa+/+ | 147.0 ± 16.7 | 150.3 ± 26.3 | 412.7 ± 15.35 | |
a
The data shown represent the mean ± SEM of two separate assays conducted on cells pooled from three mice in each group at each time point. Ab, antibody.