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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Atherosclerosis. 2022 Nov 12;363:8–21. doi: 10.1016/j.atherosclerosis.2022.11.009

Table 1.

Differences between INOCA and MINOCA.

INOCA MINOCA
Symptoms Yes Yes
Resting EKG abnormalities Possible Possible
Exercise EKG abnormalities Usually N/A*
Abnormal wall motion on stress echo Possible, but usually not N/A
Abnormal perfusion on SPECT Possible, but usually “breast artifact” or “probably normal” N/A
Abnormal PET-derived myocardial flow reserve If yes, diagnose CMD
If no, could still be CMD due to a vasocontrictor problem; definitive diagnosis requires invasive coronary function testing
N/A
Troponin elevation May have a prior history of troponin elevation, and now recurrent non-MI chest pain Yes
*

Not applicable in acute coronary syndrome