Table 1.

Kinetic Parameters Corresponding to a Single Intravenous Injection of Phenylalanine in Four Sprague-Dawley Rats

Animal	Fasted	Pre-bolus baseline (μM)[a]	Post-bolus baseline (μM)[b]	A (μM)[b]	α half life (min)[b]	B (μM)[b]	β half life (min)[b]	R2	CMAX (μM)
RAT 1	Yes	27.9±0.6	28.4±1.4	53±16	0.4±0.1	29 ±3	8.9±1.8	0.898	87
RAT 2	Yes	37.0±1.4	43.3±0.6	68±13	0.5±0.2	43±13	2.7±0.6	0.944	131
RAT 3	No	40.8±1.6	66.9±0.8	34±16	0.5±0.4	16.2±16.4	2.7±2.4	0.755	112
RAT 4	No	34.5±0.9	52.5±1.3	63±11	1.1±0.4	26±11	6.6±3.0	0.916	124
Ref. [21][c]	Yes	72±22	109±13	NA	NA	72±34	14±15	0.831	154±32

^[a]The error bars reported here are 95% confidence intervals derived from standard deviations.

^[b]The error bars reported here are 95% confidence intervals based on estimated standard errors of the fits.

^[c]Values obtained using a single exponential fit.