Table 1.
Taxa Showing a Significant Difference in Abundance in the Stool Microbiome between Patients with Inflammatory Bowel Disease and Healthy Controls
| Taxon | Log-transformation t-statistic |
FDR adjusted p-value |
|---|---|---|
| Phylum Firmicutes | ||
| Family Lachnospiraceae | 2.40 | 0.030 |
| Genus Clostridium_g21 | 3.69 | <0.001 |
| Species Ruminococcus gnavus | 3.69 | <0.001 |
| Genus Eubacterium_g5 | –7.06 | <0.001 |
| Species Eubacterium hallii | –7.06 | <0.001 |
| Genus Agathobacter | 2.50 | 0.020 |
| Species Agathobacter rectalis | 2.50 | 0.020 |
| Genus Blautia | -4.52 | <0.001 |
| Species Blautia obeum | –3.62 | 0.001 |
| Species Blautia wexlerae | –2.95 | 0.007 |
| Genus DQ057459_g | –4.47 | <0.001 |
| Genus EU457907_g | –2.53 | 0.020 |
| Genus Fusicatenibacter | –3.85 | <0.001 |
| Species Fusicatenibacter saccharivorans |
–3.85 | <0.001 |
| Genus KE159538_g | –2.40 | 0.030 |
| Genus Roseburia | 3.70 | <0.001 |
| Species Roseburia faecis | 3.52 | <0.001 |
| Species Roseburia inulinivorans | 2.37 | 0.030 |
| Genus Ruminococcus_g4 | 2.63 | 0.006 |
| Species Ruminococcus lactaris | 2.09 | 0.050 |
| Species Ruminococcus torques | 2.54 | 0.003 |
| Family Leuconostocaceae | –3.45 | <0.001 |
| Genus Weissella | –3.48 | <0.001 |
| Species Weissella cibaria | –3.19 | <0.001 |
| Species Weissella koreensis | –2.48 | 0.030 |
| Family Christensenellaceae | −3.02 | <0.001 |
| Genus AB239481_g | −3.02 | <0.001 |
| Family Mogibacterium_f | −5.65 | <0.001 |
| Family Peptostreptococcaceae | −3.14 | 0.006 |
| Genus Romboutsia | −2.80 | 0.020 |
| Family Streptococcaceae | −4.76 | <0.001 |
| Genus Streptococcus | −4.76 | <0.001 |
| Species Streptococcus oligofermentans |
−2.74 | 0.010 |
| Species Streptococcus salivarius | −2.87 | 0.010 |
| Species Streptococcus sanguinis | −2.83 | 0.008 |
| Family Veillonellaceae | 2.83 | <0.001 |
| Genus Veillonella | 2.83 | <0.001 |
| Species Veillonella dispar | 2.83 | <0.001 |
| Family Ruminococcaceae | ||
| Genus Caproiciproducens | 3.79 | <0.001 |
| Genus Faecalibacterium | 4.50 | <0.001 |
| Genus Pseudoflavonifractor | 3.70 | <0.001 |
| Species Flavonifractor plautii | 3.71 | <0.001 |
| Genus Ruminococcus_g2 | −3.38 | <0.001 |
| Species Ruminococcus bromii | −3.38 | 0.001 |
| Phylum Bacteroidetes | 6.00 | <0.001 |
| Family Bacteroidaceae | 5.37 | <0.001 |
| Genus Bacteroides | 5.37 | <0.001 |
| Species Bacteroides dorei | 1.72 | 0.040 |
| Species Bacteroides fragilis | 2.92 | 0.010 |
| Species Bacteroides ovatus | 2.55 | 0.006 |
| Species Bacteroides plebeius | 3.52 | 0.040 |
| Species Bacteroides vulgatus | 5.36 | <0.001 |
| Phylum Actinobacteria | −2.95 | 0.008 |
| Phylum Verrucomicrobia | −3.03 | 0.006 |
| Family Akkermansiaceae | −3.03 | 0.006 |
| Genus AM500802_g | −5.65 | <0.001 |
| Genus Akkermansia | −3.03 | 0.006 |
| Species Akkermansia muciniphila |
−3.03 | 0.007 |
The change of column (log transformation) shows the multiplicative change in taxa abundance between patients with inflammatory bowel disease and healthy controls. Negative numbers represent decreased abundance in patients with inflammatory bowel disease compared with healthy controls.
FDR, false discovery rate.