Table 2.
Taxa Showing a Significant Difference in the Abundance of Gut Microbe-Derived Extracellular Vesicles between Patients with Inflammatory Bowel Disease and Healthy Controls
| Taxon | Log-transformation t-statistic |
FDR adjusted p-value |
|---|---|---|
| Phylum Firmicutes | 6.61 | <0.001 |
| Family Lachnospiraceae | ||
| Genus DQ057459_g | −2.75 | 0.020 |
| Genus Fusicatenibacter | −3.63 | 0.002 |
| Species Fusicatenibacter saccharivorans |
−3.63 | 0.002 |
| Family Veillonellaceae | ||
| Genus Dialister | −2.83 | 0.009 |
| Species Dialister invisus | −2.83 | 0.009 |
| Family Ruminococcaceae | 4.59 | <0.001 |
| Genus Butyricicoccus | 2.95 | 0.006 |
| Genus Faecalibacterium | 4.66 | <0.001 |
| Genus JN713389_g | −3.23 | 0.005 |
| Genus Sporobacter | 2.51 | 0.030 |
| Family Acidaminococcaceae | −2.98 | 0.002 |
| Genus Phascolarctobacterium | −2.98 | 0.003 |
| Species Phascolarctobacterium faecium |
−2.98 | 0.003 |
| Family Enterococcaceae | 2.25 | <0.001 |
| Genus Enterococcus | 2.25 | <0.001 |
| Species Enterococcus rivorum | 2.25 | <0.001 |
| Family Lactobacillaceae | 1.83 | 0.030 |
| Genus Lactobacillus | 1.83 | 0.030 |
| Species Lactobacillus ruminis | 1.83 | 0.030 |
| Family Erysipelotrichaceae | ||
| Genus Catenibacterium | 2.32 | 0.005 |
| Genus CCMM_g | 3.10 | 0.008 |
| Genus Holdemanella | 3.18 | 0.005 |
| Phylum Actinobacteria | ||
| Family Coriobacteriaceae | 2.47 | 0.020 |
| Genus Collinsella | 2.63 | 0.009 |
| Species Collinsella aerofaciens | 2.63 | 0.009 |
| Genus Eggerthella | −2.49 | 0.020 |
| Phylum Verrucomicrobia | −6.09 | <0.001 |
| Family Akkermansiaceae | −6.09 | <0.001 |
| Genus Akkermansia | −6.09 | <0.001 |
| Species Akkermansia muciniphila |
−6.09 | <0.001 |
| Phylum Proteobacteria | −6.76 | <0.001 |
| Family Moraxellaceae | −14.98 | <0.001 |
| Genus Acinetobacter | −14.46 | 0.007 |
| Species Acinetobacter bereziniae | −15.79 | <0.001 |
| Species Acinetobacter modestus | −12.36 | <0.001 |
| Species Acinetobacter parvus | −10.97 | <0.001 |
| Species Acinetobacter johnsonii | 3.10 | <0.001 |
| Genus Klebsiella | 2.43 | <0.001 |
| Species Klebsiella granulomatis | 3.15 | <0.001 |
| Species Klebsiella variicola | 2.89 | 0.004 |
| Genus Moraxella | −4.69 | <0.001 |
| Species Moraxella osloensis | −4.69 | <0.001 |
| Family Comamonadaceae | −14.81 | <0.001 |
| Genus Diaphorobacter | −14.80 | <0.001 |
| Species Diaphorobacter nitroreducens |
−14.80 | <0.001 |
| Family Sphingomonadaceae | 4.48 | <0.001 |
| Genus Sphingomonas | 4.48 | <0.001 |
| Family Enterobacteriaceae | ||
| Genus Enterobacter | −15.95 | <0.001 |
| Species Enterobacter kobei | −15.95 | <0.001 |
The change of column (log transformation) shows the multiplicative change in taxa abundance from between patients with inflammatory bowel disease and healthy controls. Negative numbers represent decreased abundance in patients with inflammatory bowel disease compared with healthy controls.
FDR, false discovery rate.