Table 3.
Comparison of Baseline Characteristics According to the Presence of Liver Fibrosis
| Characteristics | All (n=1,180) | No fibrosis (n=1,105) | Fibrosis (n=75) | p-value |
|---|---|---|---|---|
| Age, yr | 53.27±10.33 | 53.19±10.26 | 54.45±11.26 | 0.347 |
| Sex, male/female | 844/336 | 783/322 | 61/14 | |
| Skeletal muscle mass index, % | 28.88±3.73 | 28.97±3.71 | 27.60±3.91 | 0.002 |
| Body fat mass, % | 30.08±7.41 | 29.85±7.29 | 33.52±8.40 | <0.001 |
| Body mass index, kg/m2 | 26.71±3.66 | 26.44±3.35 | 30.56±5.48 | <0.001 |
| Systolic blood pressure, mm Hg | 123.39±11.48 | 123.35±11.50 | 123.99±11.26 | 0.637 |
| Diastolic blood pressure, mm Hg | 72.59±8.65 | 72.60±8.69 | 72.49±8.06 | 0.912 |
| Fasting plasma glucose, mg/dL | 109.02±26.74 | 107.88±25.19 | 125.72±40.34 | <0.001 |
| Total cholesterol, mg/dL | 206.02±43.69 | 206.40±43.66 | 200.44±44.05 | 0.260 |
| Triglyceride, mg/dL | 172.05±120.22 | 169.11±118.22 | 215.31±140.51 | 0.007 |
| HDL-C, mg/dL | 51.45±11.64 | 51.79±11.68 | 46.43±9.82 | <0.001 |
| LDL-C, mg/dL | 131.6±34.54 | 131.75±34.66 | 129.41±32.91 | 0.555 |
| Aspartate aminotransferase, IU/L | 33.69±20.40 | 32.29±14.68 | 54.36±54.33 | 0.001 |
| Alanine aminotransferase, IU/L | 37.53±26.61 | 35.81±22.51 | 62.91±55.01 | <0.001 |
| γ-Glutamyl transferase, IU/L | 44.64±42.52 | 42.44±35.43 | 77.07±94.55 | 0.002 |
| Insulin, μIU/mL | 10.14±5.83 | 9.75±5.22 | 16.37±10.06 | <0.001 |
| Diabetes, % | 244 (20.7) | 217 (19.6) | 27 (36.0) | 0.001 |
| Smoking, % | 267 (22.6) | 243 (22.0) | 24 (32.0) | 0.001 |
| Exercise, % | 776 (65.8) | 732 (66.2) | 44 (58.7) | 0.113 |
| CAP, dB/m | 278.01±50.90 | 275.47±49.80 | 315.51±52.48 | <0.001 |
| Liver stiffness, kPa | 4.57±1.81 | 4.22±1.07 | 9.72±2.56 | <0.001 |
Data are presented as mean±SD or number (%).
HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CAP, controlled attenuation parameter.