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The mean R1 in the tumour ROIs while the patient was breathing air versus 100% oxygen for visit 1 (A, B) and visit 2 (C, D). Graphs (B) and (D) show the corresponding % change treating native R1 as baseline. The non-responder is marked in red. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
