Table 1.
Baseline Features of Patients with COVID-19 Requiring Supplemental Oxygen during Hospitalization.
| Parameters | Total (n=210) | Non-ICU (n=144) | ICU (n=66) | p value |
|---|---|---|---|---|
| Age, years | 70 (60-78) | 69 (59-78) | 72.5 (62-78) | 0.35 |
| Men, n | 15 (69.0) | 94 (65.3) | 51 (77.3) | 0.11 |
| Body mass index, kg/m 2 | 25.4 (22.2-27.8) | 24.8 (22.0-28.0) | 25.6 (23.0-26.8) | 0.97 |
| Smoking, pack-year | 8 (0-40) | 3 (0-34) | 15 (0-41) | 0.09 |
| Days from symptom onset to admission, days | 6 (4-8) | 7 (4-9) | 6 (3-8) | 0.02 |
| Comorbidities | ||||
| Hypertension, n | 112 (53.3) | 79 (54.9) | 33 (50.0) | 0.55 |
| Diabetes, n | 66 (31.4) | 43 (7.1) | 23 (34.8) | 0.52 |
| Cardiovascular disease, n | 45 (21.4) | 33 (22.9) | 12 (18.2) | 0.48 |
| Cerebrovascular disease, n | 24 (11.4) | 14 (9.7) | 10 (15.2) | 0.25 |
| Chronic kidney disease, n | 8 (3.8) | 4 (2.8) | 4 (6.1) | 0.26 |
| Chronic obstructive pulmonary disease, n | 43 (20.0) | 25 (17.4) | 18 (27.3) | 0.14 |
| Interstitial lung disease, n | 17 (8.1) | 7 (4.9) | 10 (15.2) | 0.03 |
| Malignancy, n | 7 (3.3) | 4 (2.8) | 3 (4.5) | 0.68 |
| Laboratory data | ||||
| White blood cells, ×109/L | 5.9 (4.5-7.3) | 5.9 (4.5-7.4) | 5.8 (4.4-7.0) | 0.79 |
| Lymphocytes, ×109/L | 1.0 (0.7-1.2) | 1.0 (0.7-1.2) | 0.9 (0.7-1.2) | 0.51 |
| Platelets, ×109/L | 185 (155-224) | 187 (161-231) | 176 (138-209) | 0.02 |
| Aspartate aminotransferase, IU/L | 43 (29-57) | 42 (30-56) | 44.5 (28.0-62.5) | 0.31 |
| Alanine aminotransferase, IU/L | 31 (20-48) | 31 (19-48) | 29 (20.0-49.3) | 0.84 |
| Lactate dehydrogenase, IU/L | 302 (227-389) | 295 (226-379) | 310 (242-451) | 0.17 |
| Creatine, mg/dL | 0.88 (0.71-1.04) | 0.87 (0.71-1.05) | 0.88 (0.72-1.01) | 0.97 |
| C-reactive protein, mg/dL | 6.4 (3.3-11.8) | 6.3 (3.3-11.3) | 7.5 (2.7-13.5) | 0.35 |
| D-dimer, μg/mL | 1.2 (0.9-1.7) | 1.2 (0.9-1.7) | 1.2 (0.8-1.7) | 0.80 |
| KL-6, U/mL | 316 (232-496) | 315 (229-488) | 318 (246-602) | 0.52 |
| Ferritin, ng/mL | 606 (336-1,131) | 590 (289-1,204) | 650 (463-1,097) | 0.38 |
Categorical data are presented as numbers (percentages), and continuous data as medians (interquartile range). COVID-19: coronavirus disease 2019, ICU: intensive care unit, KL-6: Krebs von den Lungen 6