Table 2.

Diagnostic time according to clinical features of EGID patients

Overall EGID patients	Diagnostic time (months) median (IQR)a	p-value
Age at symptoms onset, years	8 (3 – 11)	-
≤ 1 year	4.5 (1.5 – 10)	0.04 (1 year vs. 12 years)
1 – 5 years	12 (1 – 15)
6 – 11 years	24 (8 – 54)
≥ 12 years	12 (12 – 30)
Age at diagnosis,years	10 (6 – 13)	-
Diagnostic time, months	12 (12 –24)	-
Eosinophilic esophagitis	Diagnostic time (months) median (IQR)a	p-value
Sex
Male	12 (4.5 – 24)	0.57
Female	12 (3 – 22)
Age at symptoms onset, years	8 (3 - 12)	-
≤ 1 year	3 (1 – 6)	n.s.
1 – 5 years	12 (1 – 17.5)
6 – 11 years	12 (3.3 – 30)
≥ 12 years	12 (12 – 30)
Age at diagnosis, years	10 (4 – 14)	-
Diagnostic time, months	12 (4 – 24)	-
Comorbidities
Allergic diseases
Yes	12 (4 – 24)	0.97
No	17 (1.5 – 26)
Symptoms
Dysphagia
Yes	12 (8 – 30)	0.61
No	12 (3 – 24)
Food impaction
Yes	18 (12 – 33)	0.21
No	12 (3 – 23)
Feeding issues and reduced appetite
Yes	24 (12 – 27)	0.05
No	12 (3 – 23)
Failure to thrive
Yes	25.5 (12 – 48)	0.02
No	12 (3.5 – 23.5)
GERD-like symptoms
Yes	12 (4.5 – 24)	0.80
No	12 (3 – 24)
Nausea and vomiting
Yes	8 (1 – 21)	0.10
No	12 (12 – 24)
Abdominal pain
Yes	12 (4 – 39)	0.42
No	12 (2 – 23)
Endoscopic pattern
Fibro-stenotic patternb
Yes	12 (4 – 27)	0.90
No	12 (4 – 24)
Non-esophageal EGIDs	Diagnostic time (months) median (IQR)a	p-value
Sex
Male	18 (12 – 82.5)	0.31
Female	12 (11 – 60)
Age at symptoms onset, years	7 (3 – 11)	-
≤ 1 year	11 (11 – 11)	n.s.
1 – 5 years	12 (12 – 12)
6 – 11 years	24 (12 – 78)
≥ 12 years	12 (12 – 69)
Age at diagnosis, years	11 (6.5 – 12)	-
Diagnostic time, months	12 (12 – 69)	-
Comorbidities
Allergic diseases
Yes	18 (12 – 69)	0.87
No	12 (12 – 69)
Symptoms
Failure to thrive
Yes	90 (12 – 168)	0.53
No	12 (12 – 60)
Weight loss
Yes	12 (11 – 96)	0.67
No	18 (12 – 64.5)
Nausea and vomiting
Yes	24 (12 – 60)	0.82
No	12 (12 – 79.5)
Abdominal pain
Yes	12 (0 – 79.5)	0.82
No	24 (12 – 60)
Diarrhea
Yes	18 (12 – 51)	0.92
No	12 (12 – 90)

EGIDs eosinophilic gastrointestinal disorders, EoE eosinophilic esophagitis, IQR interquartile range, SD standard deviation

^a25^th-75^th percentiles

^bEsophageal rings and stricture