Table 5.
Correlations between the ESCC patients' clinicopathological parameters and co-expression profiles of INPP5A, HLA-G1, IL-10, and MMP-21
| Factor | Co-expression of the genes ( p value ) | ||||||
|---|---|---|---|---|---|---|---|
|
INPP5A
&
HLA-G1 |
INPP5A
&
IL-10 |
INPP5A
&
MMP-21 |
HLA-G1 & IL-10 | HLA-G1 & MMP-21 |
IL-10
&
MMP-21 |
||
| Grade of differentiation T3 | |||||||
| Pearson correlation | 0.404** | 0.477** | 0.478** | 0.296* | 0.303* | - | |
| Sig. (two-tailed) | 0.006 | 0.001 | 0.001 | 0.048 | 0.043 | - | |
| Depth of tumor invasion P.D | |||||||
| Pearson correlation | - | - | 0.935** | - | - | - | |
| Sig. (two-tailed) | - | - | 0.000 | - | - | - | |
| Lymph node metastasis node metastasis | |||||||
| Pearson correlation | - | - | 0.809** | 0.473* | - | - | |
| Sig. (two-tailed) | - | - | 0.000 | 0.017 | - | - | |
| Stage of tumor progression III | |||||||
| Pearson correlation | - | 0.799** | 0.572** | 0.582** | - | 0.483* | |
| Sig. (two-tailed) | - | 0.000 | 0.007 | 0.006 | - | 0.027 | |
*Correlation is significant at the 0.05 level; **correlation is significant at the 0.01 level (2-tailed)