Reduced scattering via SWIR CLI (900–1,700 nm) over VIS CLI (400–900 nm). (A) Left, normalized VIS CLI line intensity profiles of a 90Y source (Eppendorf, 55.5 MBq in 200 mL of saline) at increasing scattering tissue depths (chicken breast: 0, 10, and 15 mm). Full widths at half maximum increase with scattering tissue depth at 0, 10, and 15 mm with respective full widths at half maximum of 6.38, 13.05, and 33.64 mm. Right, representative VIS CLI images. (B) Left, normalized SWIR CLI line intensity profiles from the phantom setup with full widths at half maximums of 6.24, 6.40, and 7.04 mm. Right, representative SWIR CL images. In all cases, 3 separate line measurements are made from images at each depth (dotted lines), with mean shown (solid line). FWHM = full width at half maximum.