Table 2.
Simple logistic regression results in Polyautoimmunity cohort in SLE patients.
| OR | CI 95% | |
|---|---|---|
| Demographic and baseline characteristics of the disease | ||
| Age | 1,02 | 1,01 - 1,03 |
| Female sex | 0,62 | 0,35 - 1,07 |
| Duration of symptoms | 1,02 | 1,00 - 1,05 |
| Osteoporosis | 1,99 | 1,14 - 3,45 |
| Osteoarthritis | 1,33 | 0,83 - 2,16 |
| Chronic kidney disease | 0,52 | 0,20 - 1,31 |
| Ischemic heart disease | 0,93 | 0,27 - 3,15 |
| Familial autoimmunity | 1,31 | 0,41 - 4,23 |
| Symptoms and signs | ||
| Xerophthalmia | 3,92 | 2,06 - 7,48 |
| Proteinuria | 0,6 | 0,38 - 0,95 |
| Pulmonary embolism | 5,21 | 1,82 - 14,9 |
| Dry skin | 2,25 | 1,11 - 4,54 |
| Dry mouth | 3,39 | 1,97 - 5,82 |
| Oedema | 0,43 | 0,21 - 0,89 |
| Central nervous system occlusion | 11 | 2,40 - 50,26 |
| Peripheral arterial occlusion | 0,93 | 0,08 - 10,41 |
| Deep vein occlusion | 5,56 | 2,69 - 11,52 |
| Superficial venous occlusion | 1,88 | 0,11 - 30,27 |
| Treatment | ||
| Metotrexate | 1,37 | 0,81 - 2,33 |
| Antimalarials | 0,56 | 0,36 - 0,86 |
| Corticosteroids | 1,2 | 0,80 - 1,80 |
| Laboratory Results | ||
| Positive anti-dsDNA antibodies | 1,01 | 0,68 - 1,49 |
| Positive RF test | 4,25 | 1,59 - 11,29 |
| Positive aCL IgM | 2,33 | 1,22 - 4,43 |
| Positive aCL IgG | 6,67 | 2,88 - 15,46 |
| Positive Lupus anticoagulant testing | 2,78 | 1,42 - 5,41 |
| SLEDAI | 1,00 | 0,94 - 1,07 |
| SLICC Criteria | ||
| Acute cutaneous lupus | 0,80 | 0,53 - 1,22 |
| Chronic cutaneous lupus | 0,30 | 0,07 - 1,37 |
| Oral or nasal ulcers | 1,02 | 0,65 - 1,60 |
| Non- scarring alopecia | 0,80 | 0,53 - 1,21 |
| Synovitis | 1,10 | 0,73 - 1,65 |
| Serositis | 1,30 | 0,65 - 2,59 |
| Renal | 0,48 | 0,31 - 0,72 |
| Neurological | 1,90 | 0,60 - 6,01 |
| Hemolytic anemia | 1,44 | 0,83 - 2,52 |
| Lymphopenia | 1,77 | 1,20 - 2,62 |
| Thrombocytopenia | 2,54 | 1,07 - 3,20 |
| ANA positive | 2,24 | 0,82 - 6,13 |
| Anti-dsDNA | 1,01 | 0,68 - 1,49 |
| Anti-sm | 0,88 | 0,53 - 1,46 |
| Antiphospholipid Antibodies | 3,55 | 2,32 - 5,43 |
| Low complement | 1,08 | 0,73 - 1,58 |
| Positive direct Coombśtest | 2,53 | 0,56 - 1,48 |
aCL: anticardiolipin antibodies; ANA: Antinuclear Antibodies; Anti-dsDNA: Anti-double stranded DNA; Anti-SM: smith antibodies; APS: antiphospholipid syndrome; PolyA: polyautoimmunity; SD: standard deviation; RF: Rheumatoid factor; SLE: systemic lupus erythematosus; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; SLICC: Systemic Lupus International Collaborating Clinics.