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The two‐pronged study selection process. (a) Includes one publication found elsewhere; (b) one publication 29 described three eligible studies; (c) some studies (N = 14 DB and PC TRIALS and N = 6 OPEN LABEL TRIALS) reported on both safety and efficacy and are therefore included in both groups; (d) includes two studies that used “blinded” and PC designs (i.e., the type of blind employed was not specified). DB, double‐blind; PC, placebo‐controlled.
