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. 2022 Dec 22;51(1):315–336. doi: 10.1093/nar/gkac1177

Table 2.

Kinetics of excision of the Rp diastereomer of CMPαS and AMPαS by ExoN. Data were fit to a single exponential to determine the observed rate of cleavage and half-life (t1/2)

NMP Rate (min−1) t 1/2 (min)
CMP 0.22 ± 0.010 3
CMPαS (Rp,Sp) 0.0016 ± 0.0003 350
AMP 0.13 ± 0.02 5
AMPαS (Rp) 0.0015 ± 0.0003 460