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. 2022 Dec 14;66(1):804–821. doi: 10.1021/acs.jmedchem.2c01693

Table 7. In Vivo Mouse Pharmacokinetics Parameters for Selected Compounds (5 mg/kg; ip Administration).

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a

Unbound partition coefficient, Kpu,u, determined as a ratio of free brain:free plasma concentrations at 0.5 h; free concentrations for each compartment were calculated from total concentration in that compartment and the level of binding.