. 2022 Dec 30;66(1):657–676. doi: 10.1021/acs.jmedchem.2c01612

Table 3. Results of the MTT-Based Efficacy Assay⁴³ Using the Antineoplastic Agent 33 Either without or in Combination with Either Compound 24 or 30 at Concentrations of 50 nM, 100 nM, or 150 nM Using MCT1-Expressing A-549 Cells^14,15^,^a.

	A-549	A-549	A-549	A-549
	cell toxicity 33 +	cell toxicity 33 +	cell toxicity 33 +	cell toxicity 33 +
	0 nM test cmpd.	50 nM test cmpd.	100 nM test cmpd.	500 nM test cmpd.
no.	GI₅₀ ± SEM [nM]	GI₅₀ ± SEM [nM]	GI₅₀ ± SEM [nM]	GI₅₀ ± SEM [nM]
24	47.6 ± 0.7	40.0 ± 0.2	27.7 ± 0.4	19.4 ± 0.3
30	47.6 ± 0.7	38.6 ± 0.5	25.4 ± 0.4	18.6 ± 0.4

DMSO and culture medium were used to define 0 and 100%, respectively. GI₅₀ values ± SEM of at least three independent experiments are shown.

Table 3. Results of the MTT-Based Efficacy Assay43 Using the Antineoplastic Agent 33 Either without or in Combination with Either Compound 24 or 30 at Concentrations of 50 nM, 100 nM, or 150 nM Using MCT1-Expressing A-549 Cells14,15,a.