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Vaccine design and construction. (A) Graphical representation of designed vaccine constructs. (B) 3D structure of the variable and conserved vaccine constructs showing the individual genes: NTD (blue), RBD (red), HR (yellow), N (green), RdRp (orange) and P2A peptide (white). (C) Ramachandran plot analysis showing residues located in the favoured and allowed regions for structure validation.
