Skip to main content
. 2023 Jan 16;25(5):105101. doi: 10.1016/j.micinf.2023.105101

Fig. 6.

Fig. 6

Gross and histopathological analysis of the lungs from immunized Syrian hamsters challenged by SARS-CoV-2. Assessment of freshly collected lungs at 5dpi from challenged hamsters. (A) Gross pathology images from the placebo group and immunized hamsters challenged with SARS-CoV-2 delta variant. (B) Haematoxylin and Eosin (H&E) stained lung sections from the placebo group and immunized hamsters challenged with SARS-CoV-2 delta variant. (C) Gross lung images from the placebo group and immunized hamsters challenged with SARS-CoV-2 omicron variant. (D) Haematoxylin and Eosin (H&E) stained lung sections from the placebo group and immunized hamsters challenged with SARS-CoV-2 omicron variant. Gross pathology images of hamster lungs show multifocal extensive areas (yellow arrow). Infected lung tissue sections showing severe lesions of interstitial pneumonia (red circle) in the placebo group. Histopathological lesions were observed in bronchioles and adjacent alveolar spaces showing mild inflammatory changes (blue arrow).