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Structures of MERS-CoV 3CLpro in complex with cyclohexyl-containing compounds. Panels (A–C) are Fo-Fc polder omit maps (green mesh) contoured at 3σ, and hydrogen bond interactions are shown in panels D–F. The compounds are as follows: 15d (A, D), 16d (B, E), and 17d (C, F).
