The levels of p53 (A), and inflammatory cytokines TNF-α (B) and IL-6 (C) in the brain, heart, and lung tissues of rats treated with aluminum oxide nanoparticles (Al2O3-nps), zinc oxide nanoparticles (ZnO-nps), and their combination. TNF-α: Tumor necrosis factor-α; IL-6: interleukin-6. Statistical analysis was performed to measure the significant differences with p<0.05 and has been denoted as [*]. The significant differences were compared in the control and the treatment groups.