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. Author manuscript; available in PMC: 2023 Jan 16.

Published in final edited form as: J Biomed Nanotechnol. 2019 Jun 1;15(6):1241–1255. doi: 10.1166/jbn.2019.2779

Figure 5. — SiONP surfaces showed an enhanced expression of (a) SOD1 (b) Runx2 (c) Sp7 (d) Smad1 (e) Smad5 (f) OCN and (g) Col(Ⅰ)-α1 osteogenic markers for MC3T3 cells when compared to control surfaces. Maximal enhancement was observed when both the N and O were present in adequate quantities in the layer (sample 4). Moreover, MC3T3 cells showed maximum enhancement to the SiONP surface at the very initial time point (6h).

Figure 5. — SiONP surfaces showed an enhanced expression of (a) SOD1 (b) Runx2 (c) Sp7 (d) Smad1 (e) Smad5 (f) OCN and (g) Col(Ⅰ)-α1 osteogenic markers for MC3T3 cells when compared to control surfaces. Maximal enhancement was observed when both the N and O were present in adequate quantities in the layer (sample 4). Moreover, MC3T3 cells showed maximum enhancement to the SiONP surface at the very initial time point (6h).