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. 2022 Dec 22;66(1):553–576. doi: 10.1021/acs.jmedchem.2c01489

Figure 3.

Figure 3

Structures of the DOTAM and MECAM siderophores 2 and 4, TonB box peptides 510, and siderophore-peptide conjugates 1134. The conjugates consist of a siderophore unit (Tx) that is linked via a covalent or a cleavable disulfide unit (Lx) to the N-terminus or the C-terminus of the peptide (aax). Bold amino acids in 510 indicate the amino acids composing the TonB box, and framing amino acids are depicted roman.