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. 2022 Jul 5;8(1):e10371. doi: 10.1002/btm2.10371

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© 2022 The Authors. Bioengineering & Translational Medicine published by Wiley Periodicals LLC on behalf of The American Institute of Chemical Engineers.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The indocyanine green (ICG) pattern change of dorsal position in both lymphatic channel sheet (LCS) and resection limb. The patterns were observed every week for 8 weeks. They were classified based on the images below the graph, and the graph presents the normalized numerical values for the frequency of each pattern because the patterns may appear in combination. In the LCS limb, the linear pattern was maintained for 8 weeks, whereas in resection, it gradually changed to an abnormal lymph flow pattern (splash, stardust, diffuse) from 5 weeks. These results were averaged by an observer measuring three times each.