FIGURE 2.

Optimization and characterization of cell‐laden OB‐dECM hydrogel in a bone‐on‐a‐chip. (a) Viability of IDG‐SW3 cells cultured in a hydrogel with different collagen/OB‐dECM ratios on Day 3 (N = 3). (b) Representative microscopic images of hydrogel shrinkage (white dotted line with arrows) according to collagen/OB‐dECM ratios on Day 3. Scale bar represents 500 μm. (c) Young's modulus and (d) storage modulus of the optimized Col/OB‐dECM hydrogel compared to the collagen hydrogel (N = 5). All values are expressed as mean ± SD (**p < 0.01, ****p < 0.0001). OB‐dECM, osteoblast‐derived decellularized extracellular matrix