FIGURE 8.

Characterization of xeno‐free 3D bioprinted skin grafts without ECs and PCs 2‐ and 4‐week postengraftment onto immunodeficient mice. Representative images of H&E and Masson's trichome‐stained sections showing the presence of PGA mesh and high degree of necrosis in grafts lacking ECs and PCs. Delayed re‐epithelization from the wound edges was observed in grafts lacking ECs and PCs 4‐week postengraftment (black arrowheads point to large microvessels found in regions with highly dense microvascular networks). Scale bars = 100 μm. 3D, three‐dimensional; EC, endothelial cell; H&E, hematoxylin and eosin; PC, pericyte; PGA, polyglycolic acid