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. 2022 Jun 21;8(1):e10347. doi: 10.1002/btm2.10347

TABLE 2.

PANI‐based biomaterials applied in cardiac tissue engineering applications

Biomaterials Cells Main Results In vitro/in vivo References
PANI/Polyethersulfone Cardiovascular disease‐specific induced pluripotent stem cells Increased cell number +/− 224
PANI/PLGA CMs Enhanced cell adhesion +/− 225
Tetra‐aniline/PEG C2C12 Myoblast Enhanced MI regeneration +/− 226
Tetra‐aniline/PEG/hyaluronic acid Adipose‐derived stem cells (ADSCs) Enhanced endothelial and muscle cell homing, enhanced MI regeneration −/+ 227
PU/siloxane/tetra aniline CMs Enhanced cell function even without external electrical stimulation +/− 228
PANI/PLA C cell Enhanced cell viability and proliferation +/− 101
PCL‐aniline trimer C2C12 Myoblast Enhanced cell proliferation and myogenic differentiation +/− 229
Poly(citric acid‐copolycaprolactone)‐aniline hexamer C2C12 Myoblast Excellent cytocompatibility +/+ 230
Terta aniline‐ poly(n‐iso propyl acrylamide) H9c2 cells (rat cardiac myoblast) High cell viability +/+ 231
Polyurethane–aniline pentamer/PCL CMs Enhanced cell proliferation and adhesion, proper cardiac gene expression +/− 104 , 163