Table 3.
Univariate associations between childhood adversity dimensions and methylation aging measures
| Childhood methylation age | Change in methylation age | |||||
|---|---|---|---|---|---|---|
| β | 95%CI | p | β | 95%CI | p | |
| Dimensions | ||||||
| Threat | −0.02 | −0.13–0.07 | 0.58 | 0.08 | −0.01–0.16 | 0.09 |
| Material Deprivation | −0.09 | −0.19–0.01 | 0.06 | 0.07 | −0.01–0.16 | 0.09 |
| Loss | −0.06 | −0.16–0.04 | 0.23 | 0.09 | 0.00–0.18 | 0.04 |
| Unpredictability | −0.07 | −0.17–0.03 | 0.17 | 0.12 | 0.03–0.20 | 0.008 |
| Other adversities | −0.02 | −0.12–0.08 | 0.66 | 0.09 | 0.00–0.17 | 0.04 |
| Cumulative scale | −0.09 | −0.19–0.01 | 0.09 | 0.13 | 0.05–0.22 | 0.002 |
N=381. Tables represents results from 12 regression models. The childhood models were adjusted for childhood age, sex, race/ethnicity. The change in methylation age models were adjusted for adult age, time since the childhood observation, sex, and race/ethnicity. Regression coefficients are standardized.