Table 2.

Neuroplasticity of Augmented Neuromuscular Training for Left Knee and Multijoint Motor Tasks

Cluster	Brain Regionsa	Side	Voxels (No.)	P Value	Montreal Neuroimaging Institute Coordinate of Peak Voxelb			z Statistic Maximum
					x	y	z
Isolated knee movement
1	Precuneus, superior parietal cortex, and superior lateral occipital cortex	Right	964	<.001	18	−68	46	3.38
2	Lingual gyrus, precuneus intracalcarine cortex, and supracalcarine cortex	Right	461	.023	24	−64	12	3.33
3	Secondary somatosensory cortex and premotor cortex	Right	416	.040	60	4	34	3.4
Multijoint movement
1	Precentral gyrus (primary motor cortex) and postcentral gyrus (primary somatosensory cortex)	Right	380	<.001	6	−34	80	6.88

Abbreviations: FSLeyes, FSL image viewer for 3-dimensional and 4-dimensional data; FSL, Functional Magnetic Resonance Imaging of the Brain software library.

^aBrain regions with significant activation set a priori at P <.05 random-effects analysis, random field cluster–corrected for multiple comparisons, and z threshold set at z > 2.3. Anatomical regions identified with FSLeyes and FSL function atlasquery based on peak voxel location and >5% probability of cluster of activity in anatomical region based on the Harvard-Oxford Cortical Structural Atlas^17,23–25 (cluster 1 [both movements] and 2) and Juelich Histological Atlas^26–28 (cluster 3).

^bx, y, and z are based on the Montreal Neuroimaging Institute standard brain template coordinates.