Table 1.
Demographic and clinical characteristics of the patients.
| Patients (n = 59) | |
|---|---|
| Sex (Men / Woman) | 44 (74.6%) / 15 (25.4%) |
| Age (years) (Mean / median / range) | 61.2 / 63 / 20–81 |
| Time from symptoms onset to first hospital admission (days) (Mean / median / range) | 8.4 / 7 / 2–31 |
| Time from symptoms onset to brain MRI (days) (Mean / median / range) | 26 / 27 / 5–47 |
| Chest CT findings suggestive of COVID-19 | |
| Positive | 50 (84.7%) |
| Negative | 4 (6.8%) |
| Not realized | 5 (8.5%) |
| RT-PCR SARS-CoV-2 on upper or lower respiratory tract swabs | 59 (100%) |
| RT-PCR SARS-CoV-2 on CSF | |
| Positive | 3 (5.1%) |
| Negative | 33 (55.9%) |
| Not realized | 23 (39%) |
| Oxygen therapy at any time during hospitalization | 57 (96.6%) |
| Acute respiratory distress syndrome | 51 (86.4%) |
| Hospitalized in intensive care unit at time of MRI | 43 (72.9%) |
| Sedation during MRI or up to 24 h before MRI | 25 (42.4%) |
| Death up to 30 days after MRI | 6 (10.2%) |
| Medical history | |
| History of stroke | 7 (11.9%) |
| History of seizures | 3 (5.1%) |
| Other neurological history | 8 (13.6%) |
| History of autoimmune diseases | 4 (6.8%) |
| History of hematological malignancies | 3 (5.1%) |
| Symptoms at any time before MRI | |
| Headaches | 12 (20.3%) |
| Seizures | 2 (3.4%) |
| Anosmia | 7 (11.9%) |
| Ageusia | 7 (11.9%) |
| Clinical signs of corticospinal tract involvement | 16 (27.1%) |
| Disturbance of consciousness | 40 (67.8%) |
| Confusion | 25 (42.4%) |
| Agitation | 21 (35.6%) |
| Electroencephalogram | |
| Normal | 4 (6.8%) |
| Under sedation | 9 (15.3%) |
| Nonspecific | 10 (16.9%) |
| Encephalopathy | 7 (11.9%) |
| Seizures | 0 (0%) |
| Not realized | 29 (49.2%) |