Table 1.
Variables | Total | CDK5RAP3 expression | |||
---|---|---|---|---|---|
Low | High | χ2 | P | ||
Gender | 0.397 | 0.529 | |||
Male | 180 | 93 | 87 | ||
Female | 61 | 28 | 33 | ||
Age at surgery (years) | 0.359 | 0.549 | |||
>65 | 100 | 53 | 47 | ||
≤65 | 141 | 68 | 73 | ||
BMI | 0.451 | 0.502 | |||
≤25 | 202 | 22 | 17 | ||
>25 | 39 | 99 | 103 | ||
Tumour size (mm) | 1.198 | 0.274 | |||
>45 | 122 | 66 | 56 | ||
≤45 | 119 | 55 | 64 | ||
Location of primary tumour | 3.869 | 0.276 | |||
Lower 1/3 | 113 | 59 | 54 | ||
Middle 1/3 | 39 | 18 | 21 | ||
Upper 1/3 | 57 | 24 | 33 | ||
More than 1/3 | 32 | 20 | 12 | ||
Chemotherapy | 1.589 | 0.207 | |||
No | 97 | 54 | 43 | ||
Yes | 144 | 67 | 77 | ||
Degree of differentiation | 8.854 | 0.003 | |||
Well/moderate | 74 | 26 | 48 | ||
Poor and not | 167 | 95 | 72 | ||
Depth of invasion | 0.748 | 0.862 | |||
T1 | 31 | 15 | 16 | ||
T2 | 23 | 11 | 12 | ||
T3 | 99 | 53 | 46 | ||
T4 | 88 | 42 | 46 | ||
Lymph node metastasis | 4.1450 | 0.246 | |||
N0 | 63 | 32 | 31 | ||
N1 | 41 | 15 | 26 | ||
N2 | 51 | 26 | 25 | ||
N3 | 86 | 48 | 38 | ||
TNM stage | 2.297 | 0.317 | |||
I | 39 | 21 | 18 | ||
II | 62 | 26 | 36 | ||
III | 140 | 74 | 66 |
P < 0.05 marked in bold font shows statistical significance.
An IHC scores of 4 points were used to stratify tumours with low versus high CDK5RAP3 expression.