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. 2022 Aug 23;30(1):22–37. doi: 10.1038/s41417-022-00515-9

Table 1.

Relationship between CDK5RAP3 expression and baseline characteristics of patients.

Variables Total CDK5RAP3 expression
Low High χ2 P
Gender 0.397 0.529
 Male 180 93 87
 Female 61 28 33
Age at surgery (years) 0.359 0.549
 >65 100 53 47
 ≤65 141 68 73
BMI 0.451 0.502
 ≤25 202 22 17
 >25 39 99 103
Tumour size (mm) 1.198 0.274
 >45 122 66 56
 ≤45 119 55 64
Location of primary tumour 3.869 0.276
 Lower 1/3 113 59 54
 Middle 1/3 39 18 21
 Upper 1/3 57 24 33
 More than 1/3 32 20 12
Chemotherapy 1.589 0.207
 No 97 54 43
 Yes 144 67 77
Degree of differentiation 8.854 0.003
 Well/moderate 74 26 48
 Poor and not 167 95 72
Depth of invasion 0.748 0.862
 T1 31 15 16
 T2 23 11 12
 T3 99 53 46
 T4 88 42 46
Lymph node metastasis 4.1450 0.246
 N0 63 32 31
 N1 41 15 26
 N2 51 26 25
 N3 86 48 38
TNM stage 2.297 0.317
 I 39 21 18
 II 62 26 36
 III 140 74 66

P < 0.05 marked in bold font shows statistical significance.

An IHC scores of 4 points were used to stratify tumours with low versus high CDK5RAP3 expression.