Table 1.
Demographic Data of All Participants Grouped According to the Apnea/Hypopnea Index (AHI, /hr.)
| Control (N = 24) | Mild OSA (N = 51) | Moderate OSA (N = 43) | Severe OSA (N = 52) | p value | |
|---|---|---|---|---|---|
| Age (years) | 35.0 (31.5~46.0) | 38.0 (32.3~45.5) | 39.0 (32.3~46.0) | 40.0 (35.0~46.0) | 0.725 |
| Sex (Male/Female) | 7/17 | 31/20 | 31/12 | 51/1 | <0.0001* |
| BMI (kg/m2) | 23.4 (21.0~25.3) | 24.1 (22.5~26.0) | 25.6 (23.8~27.4) | 28.4 (26.1~31.1) | <0.0001* |
| ESS | 7 (6~8) | 8 (5~12) | 10 (7~13) | 9 (6~13) | 0.128 |
| AHI (/hr) | 2.7 (1.1~3.6) | 9.0 (6.5~11.7) | 20.4 (16.8~24.2) | 58.9 (45.9~69.5) | <0.0001* |
| AHI in REM (/hr) | 3.1 (0 ~12.9) | 17.4 (9.6~22.9) | 37.5 (24.3~51.0) | 56.8 (41.9~68.3) | <0.0001* |
| Arousal index | 9.1 (4.7~12.1) | 9.5 (5.3~17.3) | 23.4 (12.7~32.1) | 41.6 (25.3~59.5) | <0.0001* |
| Longest Apnea (sec) | 21.4 (17.4~33.9) | 24.1 (17.3~39.2) | 44.4 (31.5~59.5) | 59.2 (41.2~79.1) | <0.0001* |
| mO2(%) | 96.5 (94.9~97.1) | 95.8 (95.2~96.3) | 95.2 (94.4~96.1) | 93.0 (91.7~94.7) | <0.0001* |
| LSaO2 (%) | 90.5 (87.0~93.5) | 89.0 (85.3~91.0) | 82.5 (78.0~88.0) | 74.0 (63.0~78.0) | <0.0001* |
| ODI (/hr) | 1.4 (0.5~2.4) | 4.7 (3.0~7.1) | 12.5 (7.3~15.4) | 53.8 (37.0~65.8) | <0.0001* |
Notes: Continuous data were expressed as median (interquartile range) compared using Kruskal–Wallis Test and categorical data by chi-square test. *Statistically significant.
Abbreviations: OSA, obstructive sleep apnea/hypopnea syndrome; BMI, body mass index; ESS, Epworth Sleepiness Scale; AHI, apnea-hypopnea index; REM, rapid eye movement; mO2, mean saturation of oxygen; LSaO2, lowest saturation of oxygen; ODI, oxygen desaturation index.