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. 2023 Jan 16;8:31. doi: 10.1038/s41392-022-01297-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — The p53 signaling pathway and NF-κB pathway in head and neck cancer. CHK1/2 cell cycle checkpoint kinase 1/2, MDM2 murine double minute 2, CDK cyclin-dependent kinase, RB retinoblastoma, TNF tumor necrosis factor, TNFR tumor necrosis factor receptor, TLR4 Toll-like receptor 4, TRAF TNFR-associated factor, RIP receptor-interacting protein, IKK IκB kinase