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. 2023 Jan 16;8:31. doi: 10.1038/s41392-022-01297-0

Fig. 6.

Fig. 6

Comprehensive understanding and inhibitor direction for targeting signaling pathways in clinical trials in HNC treatment. EGFR epidermal growth factor receptor, MET mesenchymal–epithelial transition factor, AKT serine/threonine-specific protein kinase, mTOR mammalian target of rapamycin, CDK cyclin-dependent kinase, VEGF vascular endothelial growth factor, JAK jenus-activated kinase, STAT signal transducer and activator of transcription, mAb monoclonal antibody, RET rearranged during transfection, p phosphorylation