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. 2023 Jan 16;13:854. doi: 10.1038/s41598-023-27859-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Spatiotemporal expression of Il6st (Gp130) mRNA in the mouse uterus during early pregnancy. Signals (dark purple) are detected by an anti-sense probe (left). The sense probe (right) shows the background signal. Gp130 mRNA, which was almost undetectable at day 1 of pregnancy (D1), is expressed in the glandular epithelium (ge), but not in the luminal epithelium (le), before embryo implantation (D4), and subsequently is expressed in differentiating stromal cells and decidual cells (D5 and D8). Scale bar, 100 µm. le luminal epithelium, ge glandular epithelium, st stroma, em embryo, dec decidua.